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Question 424 of 782

Which hormone is primarily responsible for regulating blood glucose levels in the body?

  • Glucagon
  • Insulin
  • Adrenaline
  • Thyroxine

Correct Answer: B

Explanation
Correct Option: B. Insulin Detailed Explanation:
  1. Understanding Blood Glucose Regulation:
  2. Blood glucose levels are crucial for maintaining energy homeostasis in the body. The body needs a stable supply of glucose, especially for the brain and muscles, which rely heavily on glucose for energy.
  3. Role of Insulin:
  4. Insulin is a hormone produced by the beta cells of the pancreas. Its primary function is to lower blood glucose levels when they are elevated, such as after a meal.
  5. When you eat, carbohydrates are broken down into glucose, which enters the bloodstream. In response, the pancreas releases insulin.
  6. Insulin facilitates the uptake of glucose by cells, particularly in muscle and fat tissues, allowing them to use glucose for energy or store it as glycogen (in the liver and muscles) or fat (in adipose tissue).
  7. Additionally, insulin inhibits gluconeogenesis (the production of glucose from non-carbohydrate sources) and glycogenolysis (the breakdown of glycogen into glucose), further helping to lower blood glucose levels.
  8. Why Other Options Are Incorrect:
  9. A. Glucagon:
    • Glucagon is produced by the alpha cells of the pancreas and has the opposite effect of insulin. It raises blood glucose levels by promoting glycogenolysis and gluconeogenesis when blood glucose levels are low. While glucagon is important for maintaining glucose levels, it does not primarily regulate them; rather, it acts when glucose levels drop.
  10. C. Adrenaline:
    • Adrenaline (or epinephrine) is a hormone released during stress or "fight or flight" situations. It increases blood glucose levels by stimulating glycogenolysis and gluconeogenesis, but it is not the primary regulator of blood glucose under normal conditions. Its role is more about providing a quick energy source during emergencies.
  11. D. Thyroxine:
    • Thyroxine (T4) is a hormone produced by the thyroid gland that regulates metabolism and energy expenditure. While it can influence glucose metabolism indirectly by increasing the basal metabolic rate, it does not directly regulate blood glucose levels like insulin does.
Summary of Key Points:
  • Insulin is the primary hormone responsible for lowering blood glucose levels.
  • It promotes glucose uptake by cells and inhibits glucose production when levels are high.
  • Glucagon, adrenaline, and thyroxine have roles in glucose metabolism but do not primarily regulate blood glucose levels.
  • Understanding the balance between insulin and glucagon is crucial for comprehending how the body maintains glucose homeostasis.
Revision Summary:
  • Insulin lowers blood glucose levels by facilitating glucose uptake and storage.
  • Glucagon raises blood glucose levels when they are low.
  • Adrenaline and thyroxine influence metabolism but are not primary regulators of blood glucose.
  • The interplay between insulin and glucagon is essential for maintaining stable blood glucose levels.
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